"Each problem that I solved became a rule which served afterwards to solve other problems. "
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Success in this complex endeavor depends heavily on a coherent set of strategies, programs, and budgets that support the interactive research network. The principal investigator (PI), Dr. Ronald G. Tompkins, and the awardee institution, the Massachusetts General Hospital (MGH) in Boston, have the overall responsibility for scientific and technical direction as well as administration and overall operations of the multiple-site research program. The PI also insures the development of consensus on study design, uniform treatment methods, uniform research animal models, and pathways that are operative and important to better understand the body's response to injury. The PI insures the timely dissemination of information generated by the program to program participants, the wider scientific community, and the public. At the MGH, a program manager and finance manager support the principal investigator in carrying out this ambitious research program.
Seven core groups provided the foundation for Inflammation and the Host Response to Injury in the original five-year award:
In the second five-year award, a natural evolution and growth of our Program has resulted in two of our original cores being further subdivided, and one core being funded by other sources.
Each group has its own advisory committee and core director(s).